D Value And Z Value In Sterilization

As per bp 2009. The subscript after the d indicates temperature at which the d value was determined. F0 value of a saturated steam sterilization process is the lethality expressed in terms of equivalent time in minutes at a temperature of 121ºc delivered by the process to the product in its final container with reference to microorganisms possessing a z value of 10.

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Meaning with a d value of 3 minutes we d reduce our microbial population from 1 000 000 to 10 in 15 minutes flat at the temperature the autoclave specifies.

D value and z value in sterilization. By using the values for d and z corresponding to this organism a safety margin in the sterilization time is implemented. It tells us how susceptible a specific bacterial population is to changes in temperature. A disadvantage of the traditional definition of the temperature resistance coefficient z eqn 9 is the implicit temperature dependence of this coefficient. So then if we have a d value of 4 5 minutes at 150 we can calculate d values for 160 by reducing the time by 1 log.

So if it takes an increase of 10 to move the curve one log then our z value is 10. As an example if the z value of a population is 10 0 c we can simply reduce the population from a log reduction of the d value by increasing the sterilization temperature 10 0 c. 1 d 240 1 min. There s one thing of utmost.

This time to reduce the survivors by 90 is the decimal reduction d value or in fig. So the z value allows us to calculate a thermal process of equivalency if we have one d value and the z value.